Analyzing proteins in biological materials
Wageningen UR develops protocols enabling sensitive detection and targeted analysis of selective proteins in complex protein mixtures
Proteomics is an innovative technology used to analyze the proteins present in biological materials. Wageningen UR has developed a proteomics platform with state-of-the-art mass spectrometry equipment for both targeted and untargeted analysis of multi protein mixtures.
Targeted proteomic approaches involving MRM (Multiple Reaction Monitoring) mass spectrometry are rapidly emerging as an alternative to antibody based quantification methods. MRM allows absolute quantitation of (multiple) proteins in a sample. Wageningen UR has developed several MRM assays, e.g. for absolute quantification of toxic gluten proteins in wheat products and allergic epitopes in vaccines.
Wageningen UR develops protocols enabling sensitive detection and quantitation of selective proteins in complex protein mixtures like
- Characterization of enzyme product batches
- Quality control in fermentation or industrial processing
- Contaminant detection
- Detection and characterization of allergens in food products
- Detection and quantification of numerous biomarkers related to e.g. physiological status